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Guillain-Barré syndrome and fulminant encephalomyelitis following Ad26.COV2.S vaccination: double jeopardy.
Stefanou, Maria Ioanna; Karachaliou, Eleni; Chondrogianni, Maria; Moschovos, Christos; Bakola, Eleni; Foska, Aikaterini; Melanis, Konstantinos; Andreadou, Elisabeth; Voumvourakis, Konstantinos; Papathanasiou, Matilda; Boutati, Eleni; Tsivgoulis, Georgios.
  • Stefanou MI; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Karachaliou E; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Chondrogianni M; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Moschovos C; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Bakola E; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Foska A; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Melanis K; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Andreadou E; First Department of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • Voumvourakis K; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece.
  • Papathanasiou M; Second Department of Radiology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.
  • Boutati E; Second Department of Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.
  • Tsivgoulis G; Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Rimini 1, Chaidari, 12462, Athens, Greece. tsivgoulisgiorg@yahoo.gr.
Neurol Res Pract ; 4(1): 6, 2022 Feb 08.
Article in English | MEDLINE | ID: covidwho-1775381
ABSTRACT
This correspondence comments on a published article presenting a case of rhombencephalitis following SARS-CoV-2-vaccination with the mRNA vaccine BNT162b2 (Pfizer/BioNTech). We also present the case of a 47-year-old man who developed Guillain-Barré-syndrome and a fulminant encephalomyelitis 28 days after immunization with Ad26.COV2.S (Janssen/Johnson & Johnson). Based on the presented cases, we underscore the importance of clinical awareness for early recognition of overlapping neuroimmunological syndromes following vaccination against SARS-CoV-2. Additionally, we propose that that role of autoantibodies against angiotensin-converting enzyme 2 (ACE2) and the cell-surface receptor neuropilin-1, which mediate neurological manifestations of SARS-CoV-2, merit further investigation in patients presenting with neurological disorders following vaccination against SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines Language: English Journal: Neurol Res Pract Year: 2022 Document Type: Article Affiliation country: S42466-022-00172-1

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines Language: English Journal: Neurol Res Pract Year: 2022 Document Type: Article Affiliation country: S42466-022-00172-1