Medication Adherence and Associated Factors in Patients With Type 2 Diabetes: A Structural Equation Model.
Front Public Health
; 9: 730845, 2021.
Article
in English
| MEDLINE | ID: covidwho-1775860
ABSTRACT
Background:
The number of patients with type 2 diabetes (T2D) is increasing. Medication treatment is of great importance to stabilize blood glucose. Previous studies have reported that neuroticism, self-efficacy, and social support are factors associated with medication adherence, but few studies have fully investigated the mechanisms between these factors and medication adherence in patients with T2D.Purpose:
To explore the prevalence of medication adherence and the factors associated with medication adherence in patients with T2D.Methods:
A cross-sectional study consisting of 483 patients with T2D was conducted from July to December 2020. Questionnaires containing sociodemographic and clinical characteristics, the Morisky Medication Adherence Scale-8 (MMAS-8), the neuroticism subscale of the Eysenck Personality Questionnaire-Revised Short Scale (EPQ-RS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Diabetes Management Self-efficacy Scale (DMSES) were used to collect data. The structural equation model (SEM) was used to test the hypotheses.Results:
This study included 305 (63.1%) medication adherence and 178 (36.9%) medication non-adherence patients with T2D. Social support directly influenced medication adherence (ß = 0.115, P = 0.029) and indirectly influenced medication adherence through self-efficacy (ß = 0.044, P = 0.016). Self-efficacy directly influenced medication adherence (ß = 0.139, P = 0.023). Neuroticism indirectly affected medication adherence through social support (ß = -0.027, P = 0.023) and self-efficacy (ß = -0.019, P = 0.014). Moreover, there was a sequential mediating effect of social support and self-efficacy on the relationship between neuroticism and medication adherence (ß = -0.010, P = 0.012). After controlling for age and gender, similar results were obtained. The model fit indices showed a good fit.Conclusions:
The medication adherence of patients with T2D needs to be improved. Neuroticism, social support, and self-efficacy had direct or indirect effects on medication adherence in patients with T2D. Healthcare providers should comprehensively develop intervention programs based on neuroticism, social support, and self-efficacy to improve medication adherence in patients with T2D.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Diabetes Mellitus, Type 2
/
Medication Adherence
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
Front Public Health
Year:
2021
Document Type:
Article
Affiliation country:
Fpubh.2021.730845
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