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Subacute Sclerosing Panencephalitis in Children: The Archetype of Non-Vaccination.
Papetti, Laura; Amodeo, Maria Elisa; Sabatini, Letizia; Baggieri, Melissa; Capuano, Alessandro; Graziola, Federica; Marchi, Antonella; Bucci, Paola; D'Ugo, Emilio; Kojouri, Maedeh; Gioacchini, Silvia; Marras, Carlo Efisio; Nucci, Carlotta Ginevra; Ursitti, Fabiana; Sforza, Giorgia; Ferilli, Michela Ada Noris; Monte, Gabriele; Moavero, Romina; Vigevano, Federico; Valeriani, Massimiliano; Magurano, Fabio.
  • Papetti L; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Amodeo ME; Department of Pediatrics, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Sabatini L; Department of System Medicine, Tor Vergata University of Rome, Viale Oxford 81, 00133 Roma, Italy.
  • Baggieri M; Department of Pediatrics, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Capuano A; Department of System Medicine, Tor Vergata University of Rome, Viale Oxford 81, 00133 Roma, Italy.
  • Graziola F; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Marchi A; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Bucci P; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • D'Ugo E; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Kojouri M; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Gioacchini S; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Marras CE; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Nucci CG; National Measles Reference Laboratory-WHO/LabNet, Department of Infectious Diseases-Istituto Superiore di Sanità (ISS), 00165 Rome, Italy.
  • Ursitti F; Unit of Neurosurgery, Department of Neurosciences, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
  • Sforza G; Unit of Neurosurgery, Department of Neurosciences, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
  • Ferilli MAN; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Monte G; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Moavero R; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Vigevano F; Neurology Unit, Department of Neuroscience, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
  • Valeriani M; Department of System Medicine, Tor Vergata University of Rome, Viale Oxford 81, 00133 Roma, Italy.
  • Magurano F; Child Neurology and Psychiatry Unit, Department of System Medicine, Tor Vergata University of Rome, Viale Oxford 81, 00133 Rome, Italy.
Viruses ; 14(4)2022 03 31.
Article in English | MEDLINE | ID: covidwho-1776352
ABSTRACT
Subacute sclerosing panencephalitis (SSPE) is a late complication of measles virus infection that occurs in previously healthy children. This disease has no specific cure and is associated with a high degree of disability and mortality. In recent years, there has been an increase in its incidence in relation to a reduction in vaccination adherence, accentuated by the COVID-19 pandemic. In this article, we take stock of the current evidence on SSPE and report our personal clinical experience. We emphasise that, to date, the only effective protection strategy against this disease is vaccination against the measles virus.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Subacute Sclerosing Panencephalitis / COVID-19 / Measles Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Year: 2022 Document Type: Article Affiliation country: V14040733

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Subacute Sclerosing Panencephalitis / COVID-19 / Measles Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Year: 2022 Document Type: Article Affiliation country: V14040733