Your browser doesn't support javascript.
Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.
Prasad, Nikhil K; Englum, Brian R; Mayorga-Carlin, Minerva; Turner, Douglas J; Sahoo, Shalini; Sorkin, John D; Lal, Brajesh K.
  • Prasad NK; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA; Surgery Service, Veterans Affairs Medical Center, Baltimore, MD, USA.
  • Englum BR; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Mayorga-Carlin M; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA; Surgery Service, Veterans Affairs Medical Center, Baltimore, MD, USA.
  • Turner DJ; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA; Surgery Service, Veterans Affairs Medical Center, Baltimore, MD, USA.
  • Sahoo S; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA; Surgery Service, Veterans Affairs Medical Center, Baltimore, MD, USA.
  • Sorkin JD; Baltimore Veterans Affairs Medical Center, Geriatric Research Education and Clinical Center, Baltimore, MD, USA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Lal BK; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA; Surgery Service, Veterans Affairs Medical Center, Baltimore, MD, USA. Electronic address: blal@som.umaryland.edu.
Am J Surg ; 224(4): 1097-1102, 2022 10.
Article in English | MEDLINE | ID: covidwho-1777948
ABSTRACT

BACKGROUND:

There are currently no data to guide decisions about delaying surgery to achieve full vaccination.

METHODS:

We analyzed data from patients undergoing surgery at any of the 1,283 VA medical facilities nationwide and compared postoperative complication rates by vaccination status.

RESULTS:

Of 87,073 surgical patients, 20% were fully vaccinated, 15% partially vaccinated, and 65% unvaccinated. Mortality was reduced in full vaccination vs. unvaccinated (Incidence Rate Ratio 0.77, 95% CI [0.62, 0.94]) and partially vaccinated vs. unvaccinated (0.75 [0.60, 0.94]). Postoperative COVID-19 infection was reduced in fully (0.18 [0.12, 0.26]) and partially vaccinated patients (0.34 [0.24, 0.48]). Fully vaccinated compared to partially vaccinated patients, had similar postoperative mortality (1.02, [0.78, 1.33]), but had decreased COVID-19 infection (0.53 [0.32, 0.87]), pneumonia (0.75 [0.62, 0.93]), and pulmonary failure (0.79 [0.68, 0.93]).

CONCLUSIONS:

Full and partial vaccination reduces postoperative complications indicating the importance of any degree of vaccination prior to surgery.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Am J Surg Year: 2022 Document Type: Article Affiliation country: J.amjsurg.2022.03.038

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal: Am J Surg Year: 2022 Document Type: Article Affiliation country: J.amjsurg.2022.03.038