Evaluation of clinical efficacy of synthetic tannin and polidocanol-based agents and modern emollients in the hand eczema treatment. Use of new hand antiseptics during the pandemic in patients with hand eczema
Klinicheskaya Dermatologiya i Venerologiya
; 21(1):59-67, 2022.
Article
in Russian
| EMBASE | ID: covidwho-1780348
ABSTRACT
Background. Patients with hand eczema account for 30–40% of dermatological patients. With the pandemic of new coronavirus infection COVID-19 and the need for frequent antiseptics use, there has been a steady increase in hand eczema incidence. The dominant symptoms in exacerbating eczema are skin inflammation and itching, which requires effective and safe skincare that is effective and safe. Objective. To evaluate the efficacy of the therapy with synthetic tannin and polidocanol-based agents and modern emollients, the time of resolution and degree of severity of clinical symptoms of eczema in patients, as well as the time and duration of remission, safety and compliance with sodium hypochlorite hand antiseptic spray. Materials and methods. Thirty-four patients with exacerbation of hand eczema were examined. The study was conducted in two stages. At the stage 1, before the remission, the patients received synthetic tannin and polidocanol-based agents and modern emollients;at the stage 2, monotherapy with modern emollients was used. Patients used sodium hypochlorite spray as a hand sanitizer throughout the study period. Results. The NESCI score became zero in 33 (96%) patients after the complex treatment of hand eczema. The Dermatology Life Quality Index by the end of stage 2 decreased 6-fold compared to the beginning of the study. No exacerbation of the dermatosis was observed in any of the patients included in the study during the use of sodium hypochlorite hand spray. Conclusion. The complex therapy with synthetic tannin, polidocanol-based agents, and modern emollients in hand eczema helps to achieve stable medical remission, decreases the itching intensity, and improves the patients’ quality of life. The use of new hand sanitizers during the pandemic in patients with hand eczema did not result in dermatosis exacerbations.
adult; aerosol; article; clinical article; comparative effectiveness; controlled study; dermatitis; Dermatology Life Quality Index; disease exacerbation; drug safety; drug therapy; eczema; female; hand eczema; human; male; monotherapy; pandemic; pruritus; quality of life; remission; skin disease; antiinfective agent; emollient agent; hand sanitizer; hypochlorite sodium; polidocanol; tannin
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Experimental Studies
/
Prognostic study
Language:
Russian
Journal:
Klinicheskaya Dermatologiya i Venerologiya
Year:
2022
Document Type:
Article
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