Covid 19: A Comprehensive Review

ABSTRACT

There is a new public health crisis threatening the world with the emergency is a novel corona virus (2019-NCOV) or the severe acute respiratory syndrome corona virus (SARS-COV-2). Despite our advances in medicine and research, we continue to be challenged with new pathogens that pose a threat to human lives, global economic security, and the healthcare system. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that was first identified in Wuhan, Hubei province, central China, and is responsible for the 2019-20 pandemic. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome corona virus (MERS-CoV), but has lower fatality. The global response to the corona virus disease-2019 (COVID-19) pandemic and provide thoughts regarding lessons for future pandemics. The World Health Organization (WHO) declared a public health emergency of international concern on 30 January 2020, and a pandemic on 11 March 2020. Multiple variants of the virus have emerged and become dominant in many countries since 2021, with the Alpha, Beta, Gamma and Delta variants being the most virulent. As of 23 November 2021, more than 258 million cases and 5.16 million deaths have been confirmed, making the pandemi c one of the deadliest in history. This review aimed to discuss the COVID-19 disease beginning from virology, epidemiology and continuing with clinical manifestations, diagnosis, and its complications and to finish with available therapeutic options.