Research progress on the etiological characteristics of novel coronavirus and human immunodeficiency virus and their co-infection

ABSTRACT

Coronavirus disease 2019 (COVID-19) and AIDS (acquired immunodeficiency syndrome, AIDS) both belong to Class B infectious diseases, and their pathogens are novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) and human immunodeficiency virus (HIV). Although HIV infection is not a risk factor for COVID-19, recent clinical studies have shown that compared with HIV-negative COVID-19 patients, HIV-positive COVID-19 patients have a longer clinical course, especially with higher CD4 + T lymphocyte counts. Patients on low or no antiretroviral therapy (ART) were more severely ill. Therefore, this paper will compare the differences between the two viruses in terms of etiology and infection pathogenesis, and describe the immunological and virological characteristics of HIV-positive COVID-19 patients, which will be helpful for SARS-CoV-2 and HIV infection. have a clearer understanding.