Vogt-Koyanagi-Harada Disease following mRNA-1273 (Moderna) COVID-19 Vaccination.
Ocul Immunol Inflamm
; 30(5): 1250-1254, 2022 Jul.
Article
in English
| MEDLINE | ID: covidwho-1784140
ABSTRACT
PURPOSE:
To report a case of Vogt-Koyanagi-Harada (VKH) disease following mRNA-1273 (Moderna) COVID-19 vaccination.METHODS:
Retrospective case report.RESULTS:
A 50-year-old Korean woman developed bilateral serous retinal detachment 35 days after the first dose of COVID-19 mRNA vaccination (mRNA-1273, Moderna). She experienced adverse effects such as erythema and pain at the injection site, headache, myalgia, and allergy symptoms prior to ocular manifestation. She was diagnosed with Vogt-Koyanagi-Harada (VKH) disease. After treatment with oral prednisolone, the serous retinal detachment resolved and vision improved.CONCLUSION:
COVID-19 vaccination might be associated with VKH disease development, and the ingredients of the mRNA vaccine or viral peptide encoded by mRNA may have activated the immunological process and induced VKH disease.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Retinal Detachment
/
Uveomeningoencephalitic Syndrome
/
COVID-19
/
2019-nCoV Vaccine mRNA-1273
Type of study:
Case report
/
Diagnostic study
/
Observational study
Topics:
Vaccines
Limits:
Female
/
Humans
/
Middle aged
Language:
English
Journal:
Ocul Immunol Inflamm
Journal subject:
Allergy and Immunology
/
Ophthalmology
Year:
2022
Document Type:
Article
Affiliation country:
09273948.2022.2053547
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