Your browser doesn't support javascript.
The T-Cell Response to SARS-CoV-2 Vaccination in Inflammatory Bowel Disease is Augmented with Anti-TNF Therapy.
Li, Dalin; Xu, Alexander; Mengesha, Emebet; Elyanow, Rebecca; Gittelman, Rachel M; Chapman, Heidi; Prostko, John C; Frias, Edwin C; Stewart, James L; Pozdnyakova, Valeriya; Debbas, Philip; Mujukian, Angela; Horizon, Arash A; Merin, Noah; Joung, Sandy; Botwin, Gregory J; Sobhani, Kimia; Figueiredo, Jane C; Cheng, Susan; Kaplan, Ian M; McGovern, Dermot P B; Merchant, Akil; Melmed, Gil Y; Braun, Jonathan.
  • Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Xu A; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Mengesha E; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Elyanow R; Adaptive Biotechnologies, Seattle, WA, USA.
  • Gittelman RM; Adaptive Biotechnologies, Seattle, WA, USA.
  • Chapman H; Adaptive Biotechnologies, Seattle, WA, USA.
  • Prostko JC; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Frias EC; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Stewart JL; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Pozdnyakova V; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Debbas P; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Mujukian A; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Horizon AA; Center for Rheumatology Medical Group, Los Angeles, CA, USA.
  • Merin N; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Joung S; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Botwin GJ; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sobhani K; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Figueiredo JC; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Cheng S; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Kaplan IM; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Merchant A; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Melmed GY; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Braun J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Inflamm Bowel Dis ; 28(7): 1130-1133, 2022 07 01.
Article in English | MEDLINE | ID: covidwho-1784351
T-cell and antibody responses to severe acute respiratory syndrome coronavirus 2 vaccination in inflammatory bowel disease patients are poorly correlated. T-cell responses are preserved by most biologic therapies, but augmented by anti-tumor necrosis factor (anti-TNF) treatment. While anti-TNF therapy blunts the antibody response, cellular immunity after vaccination is robust.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Inflammatory Bowel Diseases / COVID-19 Topics: Vaccines Limits: Humans Language: English Journal: Inflamm Bowel Dis Journal subject: Gastroenterology Year: 2022 Document Type: Article Affiliation country: Ibd

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Inflammatory Bowel Diseases / COVID-19 Topics: Vaccines Limits: Humans Language: English Journal: Inflamm Bowel Dis Journal subject: Gastroenterology Year: 2022 Document Type: Article Affiliation country: Ibd