Case Report: Histoplasma Hepatitis Presenting as Common Bile Duct Obstruction.
Am J Trop Med Hyg
; 2022 Apr 11.
Article
in English
| MEDLINE | ID: covidwho-1786179
ABSTRACT
Histoplasma capsulatum is the most common endemic mycosis in the United States and can cause disseminated histoplasmosis in immunocompromised patients.1 Although hepatic involvement is common with histoplasmosis, it can be challenging to diagnose. We report a case of a 50-year-old woman receiving adalimumab for rheumatoid arthritis who presented with right upper quadrant pain, fever, jaundice, and dyspnea. The initial working diagnosis was biliary obstruction with potential COVID-19 infection. Endoscopic retrograde cholangiopancreatography suggested Mirizzi syndrome, but successful sphincterotomy failed to improve jaundice over subsequent days. Bronchoscopy and liver biopsy were performed, with the first revealing budding yeast and the later growing H. capsulatum. The patient improved with the initiation of itraconazole therapy.
Full text:
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Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
Language:
English
Year:
2022
Document Type:
Article
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