Non-Coding RNA in Idiopathic Interstitial Pneumonia and Covid-19 Pulmonary Fibrosis (preprint)
Research Square
; 2022.
Article
in English
| EuropePMC | ID: covidwho-1786473
ABSTRACT
Pulmonary fibrosis is the major manifestation of idiopathic interstitial pneumonia as well as post-COVID-19 complications. The pathogenesis of PF is a complex molecular process that involves many types of cells, proteins, genes, and regulatory elements. The non-coding RNA is the main regulatory element in this process which mainly includes;miRNA, circRNA, and lncRNA. These regulatory elements control the expression of many important genes and various pathways that are involved in the pathogenesis of pulmonary fibrosis. Identification and molecular mechanisms by which these non-coding RNA molecules works are very important because they do not only help to understand the molecular basis of the disease but could also serve as a potential diagnostic/prognostic marker as well as therapeutic targets. In this review, we have provided the latest findings and discussed the role of these regulatory elements in various biological processes and pathways involved in the pathogenesis of pulmonary fibrosis associated with IIPs and Covid-19.
Full text:
Available
Collection:
Databases of international organizations
Database:
EuropePMC
Language:
English
Journal:
Research Square
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS