Relationship between serum levels of procalcitonin, vitamin B12, vitamin D in patients with COVID-19

ABSTRACT

COVID-19 is a new infectious disease, for which there is currently no treatment. It is therefore necessary to explore biomarkers to determine the extent of lung lesions and disease severity. Objective. The study aimed to assess the usefulness of procalcitonin levels in the COVID-19 and to correlate them with other biomarkers. Methods. the collected the data, prospectively, all COVID-19 cases admitted in lab private (30) cases with COVID-19 pneumonia and (30) control patients had Reverse Transcription Polymerase Chain Reaction (RT-PCR) positive. laboratory analysis of inflammatory indices and organ function was accomplished for the sum total of cases and controls measured procalcitonin, CRP, B12, LDH. Result. Procalcitonin,CRP, LDH, D-dimer levels in patients groups the higher than those in the controls highly significant. Conclusion. In the early stage of COVID-19 procalcitonin levels were positively correlated with CRP, D-dimer, ferritin, LDH and negative correlated with B12.