Outcome of COVID-19 in Patients With Mantle Cell Lymphoma—Report From the European MCL Registry
HemaSphere
; 6(5), 2022.
Article
in English
| EuropePMC | ID: covidwho-1787481
ABSTRACT
Data on outcome of patients with mantle cell lymphoma (MCL) and COVID-19 infection are limited. The European MCL (EMCL) registry is a centralized registry of the EMCL network, collecting real-world information about treatments and disease courses. During the COVID-19 pandemic, additional data on MCL patients with COVID-19 infection were collected, aiming to identify risk factors for mortality from COVID-19. In our retrospective, multicenter, international study, we collected data from 63 MCL patients with a median age of 64 years (range, 44–84) in 9 countries with evidence of a COVID-19 infection between February 2020 and October 2021. The overall mortality rate was high (44.4%), especially in hospitalized patients (61%) and in patients with need for intensive care unit care (94%). Patients receiving rituximab had significantly poorer survival than patients not receiving rituximab (P = 0.04). Our data highlight the importance of prevention strategies and underline the need for effective vaccination in this vulnerable cohort.
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Collection:
Databases of international organizations
Database:
EuropePMC
Type of study:
Prognostic study
Language:
English
Journal:
HemaSphere
Year:
2022
Document Type:
Article
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