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Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo.
Li, Mengjiao; Ye, Zi-Wei; Tang, Kaiming; Guo, Liang; Bi, Wenwen; Zhang, Yuyuan; Tang, Yan-Dong; Rong, Guoguang; Sawan, Mohamad; Yin, Xin; Sun, Ren; Yuan, Shuofeng; Dang, Bobo.
  • Li M; Fudan University, Shanghai, China.
  • Ye ZW; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Tang K; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
  • Guo L; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
  • Bi W; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
  • Zhang Y; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
  • Tang YD; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
  • Rong G; Fudan University, Shanghai, China.
  • Sawan M; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Yin X; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
  • Sun R; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
  • Yuan S; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Dang B; Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
Cell Res ; 32(6): 589-592, 2022 06.
Article in English | MEDLINE | ID: covidwho-1788278

Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Topics: Variants Limits: Humans Language: English Journal: Cell Res Year: 2022 Document Type: Article Affiliation country: S41422-022-00656-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Topics: Variants Limits: Humans Language: English Journal: Cell Res Year: 2022 Document Type: Article Affiliation country: S41422-022-00656-4