Dynamics of SARS-CoV-2 Antibody Response to CoronaVac followed by Booster Dose of BNT162b2 Vaccine.

Fonseca, Marcela Helena Gambim; Pinto, Ana Carolina Matias Dinelly; Silva, Maria Francilene Souza; de Melo, Amanda Campelo Lima; Vasconcelos, Germana Silva; Dos Santos, Eduardo Ruback; de Carvalho Araújo, Fernanda Montenegro; de Andrade, Luiz Odorico Monteiro

Fonseca, Marcela Helena Gambim; Pinto, Ana Carolina Matias Dinelly; Silva, Maria Francilene Souza; de Melo, Amanda Campelo Lima; Vasconcelos, Germana Silva; Dos Santos, Eduardo Ruback; de Carvalho Araújo, Fernanda Montenegro; de Andrade, Luiz Odorico Monteiro.

Emerg Infect Dis ; 28(6): 1237-1240, 2022 06.

Article in English | MEDLINE | ID: covidwho-1789325

ABSTRACT

ABSTRACT

We evaluated the longitudinal dynamics of antibody response to the SARS-CoV-2 vaccine CoronaVac and the effect of a booster dose of BNT162b2 vaccine. We found a robust antibody response after the second dose of CoronaVac that wanes over time. The response was recovered by BNT162b2, which boosted anti-spike antibody titers.

Subject(s)

COVID-19; Vaccines; Antibodies, Viral; Antibody Formation; BNT162 Vaccine; COVID-19/prevention & control; COVID-19 Vaccines; Humans; SARS-CoV-2

Keywords

BNT162b2 vaccine; COVID-19; CoronaVac; SARS-CoV-2; antibody response; coronavirus disease; healthcare workers; respiratory infections; severe acute respiratory syndrome coronavirus 2; vaccine-preventable diseases; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Experimental Studies / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article

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