Human Health and COVID-19: Metabolome Approach

ABSTRACT

Metabolome refers to small molecules inside the biological sample. This review focuses on human health and COVID-19 from a metabolome point of view. The metabolome includes endogenous and exogenous metabolites. Endogenous metabolites contain natural compounds such as nucleic acids, amino acids, vitamins, fatty acids, and sugars. Exogenous metabolites include food additives, environmental toxicants, drugs, and xenobiotics. Human health is a physical, mental, and social well-being state without any disease. Many factors influence human health, such as human lifestyle, background, social, and economic state. The human diet provides principal nutrients in food that sustenance human life. There are 7 main nutrients (fats, proteins, minerals, carbohydrates, fiber, vitamins, and water). Human exercise is body movement that improves or sustains human physical fitness and health. Human exercise supports human growth and recovers human strength. Human sleep is a natural regular state of mind and body. It is changed consciousness and declines both sensory and muscle activities. Human sleep maintains memory, mood, and biological function. The viral shape of the crown is the reason for its name. The World Health Organization report reveals that this virus occurred first in animals (1940) then occurred in humans (2003). The COVID-19 occurred in Wuhan state in China in December 2019.There are 4 types of coronavirus Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus. The 4 known types of this virus (COVID-19, MERS, SARS-CoV, and SARS-CoV-2) are under the Betacoronavirus classification. In conclusion, the metabolome has an important role in human health and COVID-19. © 2022 by the authors.