Your browser doesn't support javascript.
Nocebo-Prone Behaviour in Patients with Autoimmune Rheumatic Diseases during the COVID-19 Pandemic.
Fragoulis, George E; Evangelatos, Gerasimos; Arida, Aikaterini; Bournia, Vasiliki-Kalliopi; Fragiadaki, Kalliopi; Karamanakos, Anastasios; Kravvariti, Evrydiki; Laskari, Katerina; Panopoulos, Stylianos; Pappa, Maria; Mitsikostas, Dimos D; Tektonidou, Maria G; Sfikakis, Petros P.
  • Fragoulis GE; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Evangelatos G; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Arida A; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Bournia VK; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Fragiadaki K; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Karamanakos A; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Kravvariti E; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Laskari K; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Panopoulos S; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Pappa M; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Mitsikostas DD; First Neurology Department, Aeginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Tektonidou MG; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
  • Sfikakis PP; First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, "Laiko" General Hospital, Athens, Greece.
Mediterr J Rheumatol ; 31(Suppl 2): 288-294, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-1791347
ABSTRACT

BACKGROUND:

The COVID-19 pandemic is associated with emotional distress and significant disruptions in health-care services. These are key players in the development of nocebo phenomena. We aimed to investigate nocebo-prone behaviour in patients with autoimmune rheumatic diseases (ARD) amid the COVID-19 pandemic-associated lockdown.

METHODS:

Consecutive patients were telephone-interviewed during the COVID-19 pandemic in Greece. Clinical and socioeconomic characteristics (eg, level of education) were recorded. For nocebo behaviour, a four-item validated questionnaire (Q-No, cut-off score>15), was used. Results were compared with pre-COVID-19 Q-No scores collected from patients followed-up in our department.

RESULTS:

Nocebo behaviour was detected in 51/500 (10.2%) individuals. In patients with nocebo behaviour, use of anti-hypertensives was less common (17.6% vs 31.8%, p=0.04), but a higher level of education was more common (58.8% vs 35.9%, p=0.002), compared with patients with Q-No score ≤15; the latter retained statistical significance in multivariate regression analysis (p=0.009, OR [95%CI] 2.29, [1.23-4.25]). Total Q-No scores were higher in the COVID-19-period compared to the pre-COVID-19 era [median (range); 12 (4-20) vs 11 (4-20), p=0.02]. Among 78 patients with available Q-No questionnaires in the pre-COVID-19 era, 11 (14.1%) displayed nocebo behaviour, which increased to 16 (20.5%) amid the COVID-19 pandemic. Interim development of nocebo behaviour was also associated with higher educational level (p=0.049, OR 3.65, 95%CI 1.005-13.268).

CONCLUSION:

A considerable proportion of ARD patients manifested nocebo-prone behaviour during the COVID-19 pandemic, which was more common among those with high educational level.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Mediterr J Rheumatol Year: 2020 Document Type: Article Affiliation country: Mjr.31.3.288

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Mediterr J Rheumatol Year: 2020 Document Type: Article Affiliation country: Mjr.31.3.288