Yeast goes viral: probing SARS-CoV-2 biology using S. cerevisiae.
Microb Cell
; 9(4): 80-83, 2022 Apr 04.
Article
in English
| MEDLINE | ID: covidwho-1791639
ABSTRACT
The budding yeast Saccharomyces cerevisiae has long been an outstanding platform for understanding the biology of eukaryotic cells. Robust genetics, cell biology, molecular biology, and biochemistry complement deep and detailed genome annotation, a multitude of genome-scale strain collections for functional genomics, and substantial gene conservation with Metazoa to comprise a powerful model for modern biological research. Recently, the yeast model has demonstrated its utility in a perhaps unexpected area, that of eukaryotic virology. Here we discuss three innovative applications of the yeast model system to reveal functions and investigate variants of proteins encoded by the SARS-CoV-2 virus.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Topics:
Variants
Language:
English
Journal:
Microb Cell
Year:
2022
Document Type:
Article
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