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A Rare Presentation of Acute Renal Failure Secondary to Rhabdomyolysis in a Patient Due to Atorvastatin Requiring Short-Term Renal Replacement Therapy.
Khan, Zahid; Ibekwe, Mildred; Abumedian, Mohammed; Yousif, Yousif; Mlawa, Gideon.
  • Khan Z; Cardiology, Royal Free Hospital, London, GBR.
  • Ibekwe M; Internal Medicine, Barking, Havering and Redbridge University Hospitals National Health Service (NHS) Trust, London, GBR.
  • Abumedian M; Geriatrics, Barking, Havering and Redbridge University Hospitals National Health Service (NHS) Trust, London, GBR.
  • Yousif Y; Internal Medicine, Barking, Havering and Redbridge University Hospitals National Health Service (NHS) Trust, London, GBR.
  • Mlawa G; Internal Medicine and Diabetes and Endocrinology, Barking, Havering and Redbridge University Hospitals National Health Service (NHS) Trust, London, GBR.
Cureus ; 14(3): e23511, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1791846
ABSTRACT
Renal failure secondary to rhabdomyolysis due to statins is quite rare. We present a case of a 57-year-old patient who developed acute renal failure due to rhabdomyolysis secondary to atorvastatin. Interestingly, this patient had a similar presentation 27 years ago requiring dialysis only once resulting in complete resolution of symptoms. He presented to the hospital generally feeling unwell and then developed generalized body ache. He had an extremely elevated creatinine kinase level of 116,000 and it went up to 145,000. His urine dip was negative for nitrites and was positive for blood and protein. He was commenced on intravenous fluids. He also had a computerized tomographic scan of the kidneys, ureters, and bladder, which showed some fat stranding around both kidneys likely inflammatory in origin. His creatinine level continue to rise despite intravenous fluids and was acidotic on blood gases. He also tested positive for COVID-19 on day 7 of admission and eventually needed dialysis. His renal functions improved to baseline post dialysis and kidney functions returned to normal. His autoimmune screen was negative and his renal functions remained normal on a follow-up visit.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Prognostic study Language: English Journal: Cureus Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Prognostic study Language: English Journal: Cureus Year: 2022 Document Type: Article