A Rare Presentation of Acute Renal Failure Secondary to Rhabdomyolysis in a Patient Due to Atorvastatin Requiring Short-Term Renal Replacement Therapy.
Cureus
; 14(3): e23511, 2022 Mar.
Article
in English
| MEDLINE | ID: covidwho-1791846
ABSTRACT
Renal failure secondary to rhabdomyolysis due to statins is quite rare. We present a case of a 57-year-old patient who developed acute renal failure due to rhabdomyolysis secondary to atorvastatin. Interestingly, this patient had a similar presentation 27 years ago requiring dialysis only once resulting in complete resolution of symptoms. He presented to the hospital generally feeling unwell and then developed generalized body ache. He had an extremely elevated creatinine kinase level of 116,000 and it went up to 145,000. His urine dip was negative for nitrites and was positive for blood and protein. He was commenced on intravenous fluids. He also had a computerized tomographic scan of the kidneys, ureters, and bladder, which showed some fat stranding around both kidneys likely inflammatory in origin. His creatinine level continue to rise despite intravenous fluids and was acidotic on blood gases. He also tested positive for COVID-19 on day 7 of admission and eventually needed dialysis. His renal functions improved to baseline post dialysis and kidney functions returned to normal. His autoimmune screen was negative and his renal functions remained normal on a follow-up visit.
acute renal failure and hemodialysis in icu; creatinine kinase. acute kidney injury; drug-related side effects and adverse reactions; ganglioneuroma retroperitoneal imaging pyelonephritis; non-anion gap metabolic acidosis; non-oliguric renal failure; renal calculi; rhabdomyolysis; statin induced rhabdomylosis
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MEDLINE
Type of study:
Case report
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Cohort study
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Prognostic study
Language:
English
Journal:
Cureus
Year:
2022
Document Type:
Article
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