Pneumomediastinum in ARDS (acute respiratory distress syndrome) caused by COVID-19 (coronavirus disease 2019): is protective lung ventilation really a weapon to our advantage?
Critical Care
; 26(SUPPL 1), 2022.
Article
in English
| EMBASE | ID: covidwho-1793862
ABSTRACT
Introduction:
In mechanically ventilated patients suffering from ARDS as a consequence of COVID-19 interstitial pneumonia, we have often noted pneumomediastinum development despite the use of protective mechanical ventilation [1]. The purpose of this study is to determine whether the incidence of pneumomediastinum in patients with COVID-19 ARDS was higher than in ARDS patients without COVID-19 and whether this difference could be attributed to barotrauma or pulmonary fragility.Methods:
We divided the patients into two groups Group A (patients with ARDS from COVID-19), Group B (patients with ARDS from other causes). All patients were admitted to ICU (intensive care unit) and treated with protective mechanical ventilation-tidal volume 4-6 ml/ kg of IBW (ideal body weight), plateau pressure ≤ 28 cmH2O, driving pressure ≤ 12-14 cmH2O.Results:
In group A, pneumomediastinum occurred in 8 of 59 patients(13.5%) while in group B in 1 of 59 (1.6%) (p < 0.001). Mortality was 58% in group A patients while 48% in group B patients (p = 0.32). In group A the mean of tidal volume used was 5.6 ± 0.7 ml/kg of IBW, the mean of plateau pressure 22 ± 5 cmH2O and driving pressure 11 ± 4 cmH2O. In group B the mean of tidal volume used was 5.9 ± 0.5 ml/kg of IBW, the mean of plateau pressure 23 ± 4 cmH2O and driving pressure 10 ± 3 cmH2O.Conclusions:
The incidence of pneumomediastinum was approximately 8 times higher in the group of patients with COVID-19 ARDS despite the use of protective ventilation. This complication could be the consequence of greater lung fragility in patients with COVID-19 ARDS rather than in barotrauma which refers to elevated transpulmonary pressure.
adult; adult respiratory distress syndrome; artificial ventilation; barotrauma; body weight; complication; conference abstract; controlled study; coronavirus disease 2019; female; human; ideal body weight; incidence; intensive care unit; major clinical study; male; mortality; pneumomediastinum; protective ventilation; tidal volume; weapon
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Critical Care
Year:
2022
Document Type:
Article
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