High flow nasal oxygen and continuous positive airway pressure therapy for COVID-19: an observational study of outcomes
Critical Care
; 26(SUPPL 1), 2022.
Article
in English
| EMBASE | ID: covidwho-1793898
ABSTRACT
Introduction:
High flow nasal oxygen (HFNO) and continuous positive airway pressure (CPAP) therapy are recognised treatments for hypoxia which were widely used throughout the COVID-19 pandemic. Large scale studies such as RECOVERY-RS [1] compared HFNO and CPAP to conventional oxygen therapy in patients suitable for mechanical ventilation. TSDFT had capacity to offer ward based HFNO/CPAP to patients deemed both suitable and not suitable for mechanical ventilation. We set out to review the outcomes of all patients who received HFNO/ CPAP for COVID-19 pneumonitis at our trust.Methods:
A retrospective observational study of all patients with COVID-19 Pneumonitis who received CPAP/HFNO was conducted at a district general hospital in South West England. Electronic records and ICD10 diagnostic codes were reviewed between September 2020 and October 2021.Results:
90 patients received HFNO or CPAP. The median age was 68 years. 50 (55%) survived to hospital discharge. Survival to hospital discharge was greater in females (71%) than males (42%). Survival decreased from 100% in the 21-30 years age group, to 33.3% in the > 70 years age group. On review of co-morbidities the overall survival rate was similar, except for patients with cardiac failure or valvular disease, of which only 4 of 19 patients survived (21%) All patients under 40 years survived to hospital discharge. There was no relationship between number of days of therapy and survival to discharge.Conclusions:
Among this cohort, survival to hospital discharge after HFNO or CPAP for COVID-19 Pneumonitis was greater in younger patients, females and those without cardiovascular failure.
oxygen; adult; aged; cardiovascular disease; cohort analysis; comorbidity; conference abstract; continuous positive airway pressure; controlled study; coronavirus disease 2019; drug therapy; England; female; general hospital; groups by age; heart failure; hospital discharge; human; ICD-10; major clinical study; male; observational study; outcome assessment; overall survival; pneumonia; retrospective study; trust; valvular heart disease
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Critical Care
Year:
2022
Document Type:
Article
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