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Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019.
Devlin, John W; O'Neal, Hollis R; Thomas, Christopher; Barnes Daly, Mary Ann; Stollings, Joanna L; Janz, David R; Ely, E Wesley; Lin, John C.
  • Devlin JW; School of Pharmacy, Northeastern University, Boston, MA.
  • O'Neal HR; Division of Pulmonary and Critical Care, Louisiana State University Health Sciences Center, Baton Rouge, LA.
  • Thomas C; Division of Pulmonary and Critical Care, Louisiana State University Health Sciences Center, Baton Rouge, LA.
  • Barnes Daly MA; Office of Quality and Clinical Effectiveness, Sutter Health, Sacramento, CA.
  • Stollings JL; Department of Pharmaceutical Services, Vanderbilt University Medical Center, Nashville, TN.
  • Janz DR; Critical Illness, Brain Dysfunction, Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN.
  • Ely EW; Section of Pulmonary/Critical Care and Allergy/Immunology, Louisiana State University Health Sciences Center, New Orleans, LA.
  • Lin JC; Critical Illness, Brain Dysfunction, Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN.
Crit Care Explor ; 2(6): e0139, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-1795099
ABSTRACT

OBJECTIVES:

The severe acute respiratory syndrome coronavirus 2 pandemic has stretched ICU resources in an unprecedented fashion and outstripped personal protective equipment supplies. The combination of a novel disease, resource limitations, and risks to medical personnel health have created new barriers to implementing the ICU Liberation ("A" for Assessment, Prevention, and Manage pain; "B" for Both Spontaneous Awakening Trials and Spontaneous Breathing Trials; "C" for Choice of Analgesia and Sedation; "D" for Delirium Assess, Prevent, and Manage; "E" for Early Mobility and Exercise; and "F" for Family Engagement and Empowerment [ABCDEF]) Bundle, a proven ICU care approach that reduces delirium, shortens mechanical ventilation duration, prevents post-ICU syndrome, and reduces healthcare costs. This narrative review acknowledges barriers and offers strategies to optimize Bundle performance in coronavirus disease 2019 patients requiring mechanical ventilation. DATA SOURCES STUDY SELECTION AND DATA EXTRACTION The most relevant literature, media reports, and author experiences were assessed for inclusion in this narrative review including PubMed, national newspapers, and critical care/pharmacology textbooks. DATA

SYNTHESIS:

Uncertainty regarding coronavirus disease 2019 clinical course, shifts in attitude, and changes in routine behavior have hindered Bundle use. A domino effect results from 1) changes to critical care hierarchy, priorities, and ICU team composition; 2) significant personal protective equipment shortages cause; 3) reduced/restricted physical bedside presence favoring; 4) increased depth of sedation and use of neuromuscular blockade; 5) which exacerbate drug shortages; and 6) which require prolonged use of limited ventilator resources. Other identified barriers include manageable knowledge deficits among non-ICU clinicians unfamiliar with the Bundle or among PICU specialists deploying pediatric-based Bundle approaches who are unfamiliar with adult medicine. Both groups have been enlisted to augment the adult ICU work force to meet demand. Strategies were identified to facilitate Bundle performance to liberate patients from the ICU.

CONCLUSIONS:

We acknowledge current challenges that interfere with comprehensive management of critically ill patients during the coronavirus disease 2019 pandemic. Rapid response to new circumstances precisely requires established safety mechanisms and protocols like the ABCDEF Bundle to increase ICU and ventilator capacity and help survivors maximize recovery from coronavirus disease 2019 as early as possible.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Qualitative research / Randomized controlled trials / Reviews Topics: Long Covid Language: English Journal: Crit Care Explor Year: 2020 Document Type: Article Affiliation country: CCE.0000000000000139

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Qualitative research / Randomized controlled trials / Reviews Topics: Long Covid Language: English Journal: Crit Care Explor Year: 2020 Document Type: Article Affiliation country: CCE.0000000000000139