Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care.
EPMA J
; 13(2): 315-334, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1797482
ABSTRACT
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer management is associated with challenges considering risk assessment and predictive diagnostics, targeted prevention of metastatic disease, appropriate treatment options, and cost-effectiveness of approaches applied. Accumulated research evidence indicates promising anti-cancer effects of phytochemicals protecting cells against malignant transformation, inhibiting carcinogenesis and metastatic spread, supporting immune system and increasing effectiveness of conventional anti-cancer therapies, among others. Molecular and sub-/cellular mechanisms are highly complex affecting several pathways considered potent targets for advanced diagnostics and cost-effective treatments. Demonstrated anti-cancer affects, therefore, are clinically relevant for improving individual outcomes and might be applicable to the primary (protection against initial cancer development), secondary (protection against potential metastatic disease development), and tertiary (towards cascading complications) care. However, a detailed data analysis is essential to adapt treatment algorithms to individuals' and patients' needs. Consequently, advanced concepts of patient stratification, predictive diagnostics, targeted prevention, and treatments tailored to the individualized patient profile are instrumental for the cost-effective application of natural anti-cancer substances to improve overall breast cancer management benefiting affected individuals and the society at large.
Breast cancer; COVID-19; Cost-effective disease management; Evidence-based research data; Food; Health risk assessment; Improved individual outcomes; Individualized patient profiling; Modifiable risk factors; Molecular patterns; Phytochemicals; Plants; Predictive Preventive Personalized Medicine (PPPM/3PM); Primary secondary tertiary care; Stroke; Translational research; Treated cancer
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Language:
English
Journal:
EPMA J
Year:
2022
Document Type:
Article
Affiliation country:
S13167-022-00277-2
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