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An Innovative Review Study on Using Pulmonary Vaccination in COVID 19 Pandemic
International Journal of Pharmaceutical Sciences Review and Research ; 73(1):120-126, 2022.
Article in English | EMBASE | ID: covidwho-1798543
ABSTRACT
The current state of pulmonary vaccine delivery will be discussed in this review. The prospects for lung immunization using dry powder generation technologies and specialized medicinal formulations are discussed. In terms of vaccine durability and antigenicity, dry powder vaccine generation technologies may be advantageous. The non-invasive, reasonably safe, and low-cost nature of pulmonary delivery could help the public health vaccination significantly. The vaccines, which are all given intramuscularly, produce systemic antibodies in the blood but not antibodies in the pulmonary mucosal lining. Inhalation vaccines provide a number of potential benefits over injectable vaccines, including ease of delivery, and even self-administration. To create a dry powder inhalation formulation that is breathable and mediates robust transfection in the lung, a safe and effective mRNA delivery vector as well as a suitable particle engineering approach is needed.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Topics: Vaccines Language: English Journal: International Journal of Pharmaceutical Sciences Review and Research Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Topics: Vaccines Language: English Journal: International Journal of Pharmaceutical Sciences Review and Research Year: 2022 Document Type: Article