Pancreatic histological studies in mice induced by alloxan and steeping okra coffee (Abelmoschus esculentus [L.] Moench)
Pharmacy Education
; 22(2):213-217, 2022.
Article
in English
| EMBASE | ID: covidwho-1798552
ABSTRACT
Introduction:
Those suffering from diabetes mellitus (DM) form one of the high-risk groups for developing severe illness from COVID-19. Steeping okra coffee (Abelmoschus esculentus [L.] Moench) is empirically used in DM treatment.Objective:
To determine the pancreatic histology in mice induced by alloxan and steeping okra coffee (SOC).Method:
This was an experimental research using 16 mice that were divided into four groups, 1) control group (alloxan and aquades) and SOC Group;2-4), treated with steeping okra coffee at 1820, 3640, and 5460 mg/KgBW concentration for ten days.Results:
The treatment groups 2 and 3 showed an improvement in the damage of acinar cells and islets of Langerhans by 100%. On the other hand, there was still 25% vacuolisation on the islets of Langerhans in the group 4 treatment group.Conclusion:
The steeping okra coffee repaired the islets of Langerhans cells and acinar cells that were vacuolised.
Full text:
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Pharmacy Education
Year:
2022
Document Type:
Article
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