SARS-CoV-2 Infection in Iranian People Living with Human Immunodeficiency Virus-1 Infection
Jundishapur Journal of Microbiology
; 15(1), 2022.
Article
in English
| EMBASE | ID: covidwho-1798772
ABSTRACT
Background:
A novel Coronavirus first emerging in Wuhan, China, was named severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). The disease caused by SARS-CoV-2 is known as Coronavirus disease 2019 (COVID-19). HIV-1 infected individuals may be at risk of COVID-19.Objectives:
This cross-sectional study evaluated the SARS-CoV-2 infection rate and COVID-19 prevalence among Iranian HIV-1-infected people.Methods:
The study was conducted on 155 HIV-1-infected patients from June 2020 to October 2020. COVID-19 Ab (IgG) was detected using an enzyme immunoassay in serum specimens. Furthermore, nasopharyngeal and oropharyngeal specimens were collected. Then, the genomic RNA of SARS-CoV-2 was detected using a real-time polymerase chain reaction (RT-PCR). Clinical symptoms of the studied participants with and without COVID-19 were examined.Results:
Of 155 HIV-1-infected individuals, 12 (7.7%) had positive real-time PCR results for SARS-CoV-2. Out of 12 (7.7%) patients with COVID-19, four (33.3%) were males. Anti-COVID Ab (IgG) was detected in 10 (6.5%) participants, of whom eight (80.0%) were males. The most common COVID-19 clinical symptoms, including dry cough, fever, runny nose, anosmia, and hypogeusia, were observed in seven (58.3%), five (41.7%), five (41.7%), five (41.7%), and five (41.7%) patients with COVID-19, respectively.Conclusions:
A recent study has shown that the risk of SARS-CoV-2 infection in HIV-infected individuals is similar to that in the general population.
adult; anosmia; article; controlled study; coronavirus disease 2019; cross-sectional study; dry cough; enzyme immunoassay; female; fever; human; Human immunodeficiency virus 1; Human immunodeficiency virus 1 infection; Human immunodeficiency virus infection; human tissue; hypogeusia; immunoglobulin blood level; infection rate; Iranian people; major clinical study; male; nonhuman; prevalence; real time polymerase chain reaction; rhinorrhea; Severe acute respiratory syndrome coronavirus 2; endogenous compound; genomic RNA; immunoglobulin G
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Jundishapur Journal of Microbiology
Year:
2022
Document Type:
Article
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