Neuroimaging findings in hospitalized patients with COVID-19
Egyptian Journal of Radiology and Nuclear Medicine
; 53(1), 2022.
Article
in English
| EMBASE | ID: covidwho-1799082
ABSTRACT
Background:
Variable neuroimaging findings have been reported in patients with coronavirus disease 2019 (COVID-19). In addition to respiratory symptoms, many neurologic manifestations of COVID-19 are increasingly reported and variable neuroimaging findings have been observed in patients with COVID-19. Our aim was to describe findings observed in hospitalized patients with COVID-19, presenting with acute neurologic manifestations and undergoing computed tomography (CT) or magnetic resonance imaging (MRI) of the brain.Methods:
We performed a retrospective study involving patients with laboratory-confirmed SARS-COV-2 infection, admitted to our hospital between July 1 and December 30, 2020. Patients who presented with acute neurologic symptoms and required neuroimaging were only included in the study. Neuroimaging examinations were evaluated for the presence of, infarction, hemorrhage and encephalopathy. The frequency of these findings was correlated with clinical variables, including presence of comorbidities, requirement for intensive care unit admission, and duration between admission and onset of neurologic signs and symptoms as documented in the hospital medical records.Results:
A total of 135 patients underwent at least one cross-sectional imaging of the brain, the median age of these patients was 63 years, and 72% were men. Disturbed level of consciousness was the most common neurologic symptom (80.7%). Acute neuroimaging findings were found in 34 patients (25.2%) including;acute ischemic infarcts (16/135;11.9%), intracranial hemorrhages (9/135, 6.7%), cerebral venous thrombosis (2/135;1.5%), posterior reversible encephalopathy syndrome (1/135;0.7%), and hypoxic-ischemic encephalopathy (6/135, 4.4%). There was no statistically significant difference in patient age (p = 0.062), sex (0.257), presence of comorbidities (p = 0.204), intensive care unit admission (p = 0.326) and duration between admission and onset of neurologic signs and symptoms (p = 0.755), in patients with positive versus negative neuroimaging studies.Conclusions:
Our study showed that cerebrovascular complications, ischemic and hemorrhagic were the most frequent imaging finding in hospitalized patients with COVID-19. Knowledge about these potentially serious complications can help optimize management for these patients.
gadolinium pentetate meglumine; adult; article; brain disease; brain hemorrhage; brain infarction; cerebral sinus thrombosis; comorbidity; comparative study; computer assisted tomography; controlled study; coronavirus disease 2019; disease association; female; hospital admission; hospital patient; hospitalization; human; hypoxic ischemic encephalopathy; intensive care unit; major clinical study; male; medical record; middle aged; multidetector computed tomography; neuroimaging; neurologic disease; nuclear magnetic resonance imaging; posterior reversible encephalopathy syndrome; retrospective study
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Egyptian Journal of Radiology and Nuclear Medicine
Year:
2022
Document Type:
Article
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