The rising burden of invasive fungal infections in COVID-19, can structured CT thorax change the game
Egyptian Journal of Radiology and Nuclear Medicine
; 53(1), 2022.
Article
in English
| EMBASE | ID: covidwho-1799083
ABSTRACT
Background:
The occurrence of invasive fungal infections in COVID-19 patients is on surge in countries like India. Several reports related to rhino-nasal-sinus mucormycosis in COVID patients have been published in recent times;however, very less has been reported about invasive pulmonary fungal infections caused mainly by mucor, aspergillus or invasive candida species. We aimed to present 6 sputum culture proved cases of invasive pulmonary fungal infection (four mucormycosis and two invasive candidiasis) in COVID patients, the clues for the diagnosis of fungal invasion as well as difficulties in diagnosing it due to superimposed COVID imaging features. Case presentation The HRCT imaging features of the all 6 patients showed signs of fungal invasion in the form of cavities formation in the pre-existing reverse halo lesions or development of new irregular margined soft tissue attenuating growth within the pre-existing or in newly formed cavities. Five out of six patients were diabetics. Cavities in cases 1, 2, 3 and 4 of mucormycosis were aggressive and relatively larger and showed relatively faster progression into cavities in comparison with cases 5 and 6 of invasive candidiasis.Conclusion:
In poorly managed diabetics or with other immunosuppressed conditions, invasive fungal infection (mucormycosis, invasive aspergillosis and invasive candidiasis) should be considered in the differential diagnosis of cavitary lung lesions.
amphotericin B; antibiotic agent; antifungal agent; antivirus agent; C reactive protein; D dimer; dexamethasone; enoxaparin; insulin; multivitamin; oral antidiabetic agent; steroid; adult; aged; arthralgia; article; assisted ventilation; case report; chronic kidney failure; clinical article; comorbidity; controlled study; coronavirus disease 2019; coughing; diabetes mellitus; dyspnea; fever; follow up; ground glass opacity; home quarantine; human; invasive candidiasis; male; middle aged; mucormycosis; pleura effusion; pneumothorax; soft tissue; sore throat; sputum culture; tachypnea; x-ray computed tomography
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Egyptian Journal of Radiology and Nuclear Medicine
Year:
2022
Document Type:
Article
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