Apparent lack of association of COVID-19 vaccination with Herpes Zoster.
Am J Ophthalmol Case Rep
; 26: 101549, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1800222
ABSTRACT
Purpose:
Herpes zoster (HZ) has been identified as a potential association with the BNT162b2 COVID-19 vaccination. This study evaluated this possible association in a cohort of patients receiving the vaccination.Methods:
Epic electronic health records of adult patients who received at least one COVID-19 vaccination between January 12, 2020 and 9/30/2021 within the NYU Langone Health were reviewed to analyze a new diagnosis of herpes zoster within 3 months before compared to 3 months after vaccination.Results:
Of the 596,111 patients who received at least one COVID-19 vaccination, 716 patients were diagnosed with HZ within three months prior to vaccination, compared to 781 patients diagnosed within 3 months afterwards. Using the chi-square test for independence of proportions, there was not a statistically significant difference in frequency of HZ before (proportion 0.0012, 95% CI [0.0011, 0.0013]) vs. after vaccination (proportion 0.0013, 95% CI [0.0012, 0.0014]); (p = 0.093). Conclusions and importance This study did not find evidence of an association between COVID-19 vaccination and a new diagnosis of HZ. We encourage health care professionals to strongly recommend COVID-19 vaccinations per Centers for Disease Control (CDC) recommendations and vaccination against HZ according to Food and Drug Administration (FDA) approval for the recombinant zoster vaccine.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Language:
English
Journal:
Am J Ophthalmol Case Rep
Year:
2022
Document Type:
Article
Affiliation country:
J.ajoc.2022.101549
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