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Seroprevalence of SARS-COV-2 antibodies among health-care workers exposed to COVID-19 patients in a large reference hospital, Iran.
Pagheh, Abdol Sattar; Asghari, Arghavan; Abrari Romenjan, Khadijeh; Mousavi, Tahoora; Abedi, Farshid; Ziaee, Arash; Malakimoghadam, Hakime; Ziaee, Masood.
  • Pagheh AS; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
  • Asghari A; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
  • Abrari Romenjan K; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
  • Mousavi T; Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Abedi F; Molecular and Cell Biology Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.
  • Ziaee A; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
  • Malakimoghadam H; Department of Neuroscience, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Ziaee M; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Iran J Microbiol ; 14(2): 138-144, 2022 Apr.
Article in English | MEDLINE | ID: covidwho-1884819
ABSTRACT
Background and

Objectives:

Health care workers (HCWs) are a high-risk group for acquiring and transmitting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Aim of the study was the evaluation of seroprevalence of SARS-CoV-2 in a random sample of HCWs at a large acute care hospital in Iran. Materials and

Methods:

We collected blood samples of 180 medical staffs from September 22, 2020 to January 26, 2021. The enzyme linked immunosorbent assays (ELISA) tests were used for evaluation of the presence of IgG antibodies. Participants completed a self-report questionnaire, comprising demographics, occupational, the work area, and personal protection data.

Results:

Of the 180 HCWs who participated in this study, 44 (24.4%) were seropositive for anti-SARS-CoV-2 IgG. The percentage of IgG positivity was higher in males than females (P<0.05). Also, there was statistically significant difference between presence of the antibodies and the occupation, location, and infecting family members with Covid -1 (P<0.05). Other factors did not associate significantly to antibody presence against SARS-CoV-2 (P>0.05).

Conclusion:

According to this point that the number of COVID-19 cases is still growing rapidly among HCWs. So, the epidemiological estimate of SARS-CoV-2 infection remains a major challenge that is needed to prevent the spread of infection in the hospitals.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Iran J Microbiol Year: 2022 Document Type: Article Affiliation country: Ijm.v14i2.9178

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Iran J Microbiol Year: 2022 Document Type: Article Affiliation country: Ijm.v14i2.9178