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Therapeutic potential of ciclesonide inahalation for COVID-19 pneumonia: Report of three cases.
Iwabuchi, Keisuke; Yoshie, Koichiro; Kurakami, Yuichi; Takahashi, Kota; Kato, Yoshio; Morishima, Tsuneo.
  • Iwabuchi K; Department of General Medicine, Kanagawa Prefectural Ashigarakami Hospital, Japan. Electronic address: iwabuchi@ashigarakami-hospital.jp.
  • Yoshie K; Department of General Medicine, Kanagawa Prefectural Ashigarakami Hospital, Japan.
  • Kurakami Y; Department of General Medicine, Kanagawa Prefectural Ashigarakami Hospital, Japan.
  • Takahashi K; Department of General Medicine, Kanagawa Prefectural Ashigarakami Hospital, Japan.
  • Kato Y; Department of General Medicine, Kanagawa Prefectural Ashigarakami Hospital, Japan.
  • Morishima T; Aichi Medical University (Principal Investigator of AMED "Study on Diagnosis and Treatment Methods for Serious Viral Respiratory Infections"), Japan. Electronic address: tmorishima@aichi-med-u.ac.jp.
J Infect Chemother ; 26(6): 625-632, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-180418
ABSTRACT
No specific and effective anti-viral treatment has been approved for COVID-19 so far. Systemic corticosteroid has been sometimes administered to severe infectious diseases combined with the specific treatment. However, as lack of the specific anti-SARS-CoV-2 drug, systemic steroid treatment has not been recommended for COVID-19. We report here three cases of the COVID-19 pneumonia successfully treated with ciclesonide inhalation. Rationale of the treatment is to mitigate the local inflammation with inhaled steroid that stays in the lung and to inhibit proliferation of the virus by antiviral activity. Larger and further studies are warranted to confirm the result of these cases.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnenediones / Coronavirus Infections / Glucocorticoids Type of study: Case report Limits: Aged / Female / Humans / Male Language: English Journal: J Infect Chemother Journal subject: Microbiology / Drug Therapy Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnenediones / Coronavirus Infections / Glucocorticoids Type of study: Case report Limits: Aged / Female / Humans / Male Language: English Journal: J Infect Chemother Journal subject: Microbiology / Drug Therapy Year: 2020 Document Type: Article