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COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies.
Fabbri, Viscardo P; Riefolo, Mattia; Lazzarotto, Tiziana; Gabrielli, Liliana; Cenacchi, Giovanna; Gallo, Carmine; Aspide, Raffaele; Frascaroli, Guido; Liguori, Rocco; Lodi, Raffaele; Tonon, Caterina; D'Errico, Antonietta; Foschini, Maria Pia.
  • Fabbri VP; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40139 Bologna, Italy.
  • Riefolo M; Department of Experimental, Diagnostic and Specialty Medicine, Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
  • Lazzarotto T; Department of Experimental, Diagnostic and Specialty Medicine, Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
  • Gabrielli L; Operative Unit of Clinical Microbiology, Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
  • Cenacchi G; Operative Unit of Clinical Microbiology, Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
  • Gallo C; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40139 Bologna, Italy.
  • Aspide R; Unit of Anatomic Pathology, Department of Oncology, Bellaria Hospital, Via Altura 3, 40139 Bologna, Italy.
  • Frascaroli G; Anesthesia and Neurointensive Care Unit, IRCCS Institute of Neurological Science of Bologna, Via Altura 3, 40139 Bologna, Italy.
  • Liguori R; Intensive Unit Care, Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
  • Lodi R; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40139 Bologna, Italy.
  • Tonon C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 3, 40139 Bologna, Italy.
  • D'Errico A; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40139 Bologna, Italy.
  • Foschini MP; Functional and Molecular Neuroimaging Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.
Biomolecules ; 12(5)2022 04 25.
Article in English | MEDLINE | ID: covidwho-1809689
ABSTRACT
Neurological symptoms are increasingly recognized in SARS-CoV-2 infected individuals. However, the neuropathogenesis remains unclear and it is not possible to define a specific damage pattern due to brain virus infection. In the present study, 33 cases of brain autopsies performed during the first (February-April 2020) and the second/third (November 2020-April 2021) pandemic waves are described. In all the cases, SARS-CoV-2 RNA was searched. Pathological findings are described and compared with those presently published.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study Limits: Adult / Humans Language: English Year: 2022 Document Type: Article Affiliation country: Biom12050629

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study Limits: Adult / Humans Language: English Year: 2022 Document Type: Article Affiliation country: Biom12050629