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Ischemic Stroke and SARS-CoV-2 Infection: The Bidirectional Pathology and Risk Morbidities.
Chavda, Vishal; Chaurasia, Bipin; Fiorindi, Alessandro; Umana, Giuseppe E; Lu, Bingwei; Montemurro, Nicola.
  • Chavda V; Department of Pathology, Stanford School of Medicine, Stanford University Medical Center, San Francisco, CA 94305, USA.
  • Chaurasia B; Department of Neurosurgery, Bhawani Hospital and Research Center, Birgunj 44300, Nepal.
  • Fiorindi A; Neurosurgery, SpedaliCivili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25100 Brescia, Italy.
  • Umana GE; Department of Neurosurgery, Trauma and Gamma-Knife Center, Cannizzaro Hospital, 95100 Catania, Italy.
  • Lu B; Department of Pathology, Stanford School of Medicine, Stanford University Medical Center, San Francisco, CA 94305, USA.
  • Montemurro N; Department of Neurosurgery, Azienda Ospedaliera Universitaria Pisana (AOUP), University of Pisa, 56100 Pisa, Italy.
Neurol Int ; 14(2): 391-405, 2022 Apr 24.
Article in English | MEDLINE | ID: covidwho-1810056
ABSTRACT
Stroke is a fatal morbidity that needs emergency medical admission and immediate medical attention. COVID-19 ischemic brain damage is closely associated with common neurological symptoms, which are extremely difficult to treat medically, and risk factors. We performed literature research about COVID-19 and ischemia in PubMed, MEDLINE, and Scopus for this current narrative review. We discovered parallel manifestations of SARS-CoV-19 infection and brain ischemia risk factors. In published papers, we discovered a similar but complex pathophysiology of SARS-CoV-2 infection and stroke pathology. A patient with other systemic co-morbidities, such as diabetes, hypertension, or any respiratory disease, has a fatal combination in intensive care management when infected with SARS-CoV-19. Furthermore, due to their shared risk factors, COVID-19 and stroke are a lethal combination for medical management to treat. In this review, we discuss shared pathophysiology, adjuvant risk factors, challenges, and advancements in stroke-associated COVID-19 therapeutics.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study / Reviews Language: English Journal: Neurol Int Year: 2022 Document Type: Article Affiliation country: Neurolint14020032

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study / Reviews Language: English Journal: Neurol Int Year: 2022 Document Type: Article Affiliation country: Neurolint14020032