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Features of fragile people with SARS-CoV-2 infection in isolation in a COVID-19 hotel in Rome, Italy.
Stingone, C; Latini, A; Gianserra, L; Salvi, M; Donà, M G; Giuliani, E; Lesnoni La Parola, I; Mussi, A; Cameli, N; Garelli, V; Giuliani, M; Buonomini, A R; Vujovic, B; Cerimele, M; Morrone, A.
  • Stingone C; STI/HIV Unit, San Gallicano Dermatological Institute IRCCS, Rome, Italy. mariagabriella.dona@ifo.it.
Eur Rev Med Pharmacol Sci ; 26(7): 2631-2638, 2022 04.
Article in English | MEDLINE | ID: covidwho-1811985
ABSTRACT

OBJECTIVE:

Temporary COVID-19 hotels have been established in Italy to assist the homeless people that test positive for SARS-CoV-2 and require isolation. This observational study aimed to investigate the characteristics of the subjects who were isolated at the Casa tra Noi COVID-19 hotel in Rome between October 2020 and May 2021 and to estimate the duration of SARS-CoV-2 positivity according to their main socio-demographic, behavioural and clinical features. SUBJECTS AND

METHODS:

Socio-demographic data, clinical history, and anamnestic data of guests were collected by the clinicians reviewing the medical documentation and face-to-face interviewing. Nasopharyngeal swabs were performed every 7 days and the presence of SARS-CoV-2 was assessed by RT-PCR. Median duration of SARS-CoV-2 positivity according to socio-demographic, behavioral factors and clinical condition was calculated.

RESULTS:

The 196 guests (161 males, 82.1%) had a median age of 41 years (IQR 30-53), and were mostly African (87, 44.4%). Only asymptomatic/paucisymptomatic infections were observed. Almost half of the individuals (84, 42.9%) were affected by at least one co-morbidity, the frequency of which was higher among women (57.1% vs. 39.8%, p=0.06). The date of the negative SARS-CoV-2 molecular test was known for 144 guests (73.5%). Among these, the median duration of positivity was 21 days (IQR 14-26) and did not significantly vary with age, country of origin, smoking status, alcohol or drug abuse. Among the co-morbidities, only infectious diseases significantly modified the duration of positivity, which increased from 21 to 34 days (p=0.013).

CONCLUSIONS:

Hotel guests were frequently affected by physical/mental co-morbidities. Duration of SARS-CoV-2 positivity was significantly prolonged only in individuals affected by an infectious disease.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study / Qualitative research Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur Rev Med Pharmacol Sci Journal subject: Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: Eurrev_202204_28501

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study / Qualitative research Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur Rev Med Pharmacol Sci Journal subject: Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: Eurrev_202204_28501