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Surge of Bell's Palsy in the era of COVID-19: Systematic review.
Gupta, Sonia; Jawanda, Manveen Kaur.
  • Gupta S; Department of Oral Pathology, Microbiology, and Forensic Odontology, Rayat and Bahra Dental College and Hospital, Mohali, Punjab, India.
  • Jawanda MK; Department of Oral Pathology, Microbiology, and Forensic Odontology, Laxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India.
Eur J Neurol ; 29(8): 2526-2543, 2022 08.
Article in English | MEDLINE | ID: covidwho-1816547
ABSTRACT
BACKGROUND AND

PURPOSE:

With the progression of coronavirus infectious disease 2019 (COVID-19), various neurological manifestations have been noticed in infected patients, and Bell's Palsy (BP) is one of the peripheral neuropathies among those. BP has been associated with various other viral agents. Its evidence in patients with COVID-19 signifies the possibility of association between BP and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This research was undertaken to evaluate the number of published cases of BP as the only major neurological manifestation in patients with COVID-19 from March 2020 to December 2021 and to investigate the association of SARS-CoV-2 and BP.

METHODS:

A systematic review of the published English literature was performed using an electronic search in the PubMed/Medline, Scopus, Research Gate, Research Square, and Google Scholar databases, using keywords such as "COVID-19" OR/AND "SARS-CoV-2" OR/AND "Bell's palsy" OR/AND "facial nerve palsy" OR/AND "neurological" OR/AND "manifestation".

RESULTS:

The search strategy revealed 32 relevant publications with a total of 46 patients. BP was the initial manifestation in 37% of cases, and in 63% of cases it developed after COVID-19 symptoms; 71.7% of cases showed complete recovery, and 21.7% showed only partial relief from BP.

CONCLUSIONS:

Although the number of documented cases in this research is low, evidence of BP as the only major neurological manifestation in patients with COVID-19 signifies an important clinical finding and the possibility of another viral etiology of BP. More evidence is needed to establish the exact correlation between these two entities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / Peripheral Nervous System Diseases / Bell Palsy / Facial Paralysis / COVID-19 Type of study: Diagnostic study / Etiology study / Experimental Studies / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: Eur J Neurol Journal subject: Neurology Year: 2022 Document Type: Article Affiliation country: Ene.15371

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / Peripheral Nervous System Diseases / Bell Palsy / Facial Paralysis / COVID-19 Type of study: Diagnostic study / Etiology study / Experimental Studies / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: Eur J Neurol Journal subject: Neurology Year: 2022 Document Type: Article Affiliation country: Ene.15371