Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia.
Ther Adv Infect Dis
; 9: 20499361221095731, 2022.
Article
in English
| MEDLINE | ID: covidwho-1817089
ABSTRACT
Background:
Coronavirus disease-2019 (COVID-19) is a potentially life-threatening illness with no established treatment. Cardiovascular risk factors (CRFs) exacerbate COVID-19 morbidity and mortality.Objective:
To determine the prevalence of CRF and clinical outcomes of patients hospitalized with COVID-19 in a tertiary hospital in Somalia.Methods:
We reviewed the medical records of patients aged 18 years or older with a real-time polymerase chain reaction (RT-PCR)-confirmed COVID-19 hospitalized at the De Martino Hospital in Mogadishu, Somalia, between March and July 2020.Results:
We enrolled 230 participants; 159 (69.1%) males, median age was 56 (41-66) years. In-hospital mortality was 19.6% (n = 45); 77.8% in the intensive care unit (ICU) compared with 22.2%, in the general wards (p < 0.001). Age ⩾ 40 years [odds ratio (OR) 3.6, 95% confidence interval (CI) 1.2-10.6, p = 0.020], chronic heart disease (OR 9.3, 95% CI 2.2-38.9, p = 0.002), and diabetes mellitus (OR 3.2, 95% CI 1.6-6.2, p < 0.001) were associated with increased odds of mortality. Forty-three (18.7%) participants required ICU admission. Age ⩾ 40 years (OR 7.5, 95% CI 1.7-32.1, p = 0.007), diabetes mellitus (OR 3.2, 95% CI 1.6-6.3, p < 0.001), and hypertension (OR 2.5, 95% CI 1.2-5.2, p = 0.014) were associated with ICU admission. For every additional CRF, the odds of admission into the ICU increased threefold (OR 2.7, 95% CI 1.2-5.2, p < 0.001), while the odds of dying increased twofold (OR 2.1, 95% CI 1.3-3.2, p < 0.001).Conclusions:
We report a very high prevalence of CRF among patients hospitalized with COVID-19 in Somalia. Mortality rates were unacceptably high, particularly among those with advanced age, underlying chronic heart disease, and diabetes.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Ther Adv Infect Dis
Year:
2022
Document Type:
Article
Affiliation country:
20499361221095731
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