Roles of ginsenosides in sepsis.
J Ginseng Res
; 47(1): 1-8, 2023 Jan.
Article
in English
| MEDLINE | ID: covidwho-2237361
ABSTRACT
The herbal medication Panax ginseng Meyer has widespread use in China, Korea, and other parts of the world. The main constituents of ginseng are ginsenosides, which include over 30 different triterpene saponins. It has been found that ginsenosides and their metabolites including Rg1, compound K, Rb1, Re, Rg3, and Rg5 exert anti-inflammatory activities by binding to the glucocorticoid receptor, modulating inflammation-related signaling, including NF-κB and MAPK signaling, and reducing levels of pro-inflammatory cytokines. Here, we review the recent literature on the molecular actions of ginsenosides in sepsis, suggesting ways in which they may be used to prevent and treat the disease.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Topics:
Traditional medicine
Language:
English
Journal:
J Ginseng Res
Year:
2023
Document Type:
Article
Affiliation country:
J.jgr.2022.05.004
Similar
MEDLINE
...
LILACS
LIS