MULTISYSTEM INFLAMMATORY SYNDROME IN AN INFANT WITH NEGATIVE SARS-COV-2 RT-PCR AND ANTIBODIES
Osteopathic Family Physician
; 13(3):35-39, 2021.
Article
in English
| EMBASE | ID: covidwho-1822742
ABSTRACT
Since the declaration of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in March 2020 by the World Health Organization (WHO), there has been an emergence of a new syndrome termed multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. MIS-C is defined by the presence of fever, systemic inflammation and multiorgan dysfunction in association with SARS-CoV-2 infection or COVID-19 exposure. Knowledge of this syndrome’s presentation and pathophysiology is constantly evolving as more cases are reported in the literature. This case identifies a 3-month-old patient who tested negative for SARS-CoV-2 antigen, reverse transcriptase polymerase chain reaction (RT-PCR) and antibodies but qualified for MIS-C diagnosis. To the best of our knowledge and through extensive research at the time of diagnosing and reporting this condition to the healthcare authorities, we report the youngest pediatric patient with MIS-C diagnosis. We document this case to contribute to further understanding the variable manifestations of MIS-C and the importance of early diagnosis and treatment with intravenous immunoglobulin (IVIG).
article; case report; child; clinical article; communicable disease; coronavirus disease 2019; diagnosis; early diagnosis; female; human; infant; male; nonhuman; pediatric multisystem inflammatory syndrome; pediatric patient; pediatrics; reverse transcription polymerase chain reaction; Severe acute respiratory syndrome coronavirus 2; systemic inflammatory response syndrome; antigen; human immunoglobulin
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Osteopathic Family Physician
Year:
2021
Document Type:
Article
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