Ethnomedicinal, phytochemistry and pharmacological actions of leaf extracts of Spondias mombin: a narrative review
African Journal of Biomedical Research
; 25(1):1-11, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-1823762
ABSTRACT
Spondias mombin is one of the species belonging to the (Family Anacardiaceae), its ethnomedicinal uses may be justified through many studies that reported potential pharmacological properties due to its phytochemical compounds. This review aimed at examining the ethnomedicinal uses, phytochemical compounds and pharmacological properties of S. mombin leaf extracts on the African continent, to justify its use in the management and/ or treatment of viral infections and cancers. Electronic databases such as Google Scholar, SciHub, PubMed and Science Direct with search dates between 1999 and 2019 were used. Findings from this review confirm the ethnomedicinal uses, of decoctions and infusions of S. mombin leaf extracts for management diseases such as malaria, sore throat, and inflammation disorders;studies confirmed the presence of phytochemical compounds such as Geraniin, 2-O-Caffeoyl-(+)-allohydroxycitric acid, Quercetin-3-O-beta-D-glucopyranoside and pelandjuaic acid, responsible for the antiviral and chemotherapeutic properties. However, there is a need for bio-assay guided extractions, isolation, identification and characterization of phytochemical compound(s) in the leaf extracts of S. mombin that may be responsible for antiviral and anticancer activity. Investigations of the pharmacological action, in silico and in vitro studies of known and /or newly isolated compounds are warranted in the management and /or treatment of viral infections such as, Severe Acute Respiratory Syndrome Coronavirus 2, and cancers to justify the use of leaf extracts of S. mombin on the African continent for the management of viral infections and or cancer.
Horticultural Crops [FF003]; Plant Composition [FF040]; Pesticides and Drugs; Control [HH405]; Non-wood Forest Products [KK540]; Non-food/Non-feed Plant Products [SS200]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Animal and in vitro Models for Pharmaceuticals [VV450]; plant extracts; medicinal plants; non-wood forest products; traditional medicines; leaves; reviews; pharmacology; malaria; inflammation; plant composition; chemical composition; antiviral properties; anticancer properties; viral diseases; coronavirus disease 2019; neoplasms; wild relatives; protozoal infections; parasites; infections; parasitoses; Spondias mombin; Severe acute respiratory syndrome coronavirus 2; plants; Plasmodium; Africa; Spondias; Anacardiaceae; Sapindales; eudicots; angiosperms; Spermatophyta; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Plasmodiidae; Haemospororida; Apicomplexa; Protozoa; drug plants; medicinal herbs; officinal plants; minor forest products; non-timber forest products; chemical constituents of plants; anti-viral properties; anti-cancer properties; viral infections; SARS-CoV-2; cancers; protozoal diseases; parasitosis; parasitic diseases; parasitic infestations
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Reviews
Language:
English
Journal:
African Journal of Biomedical Research
Year:
2022
Document Type:
Article
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