Myocarditis

ABSTRACT

Myocarditis, inflammation of the muscular portion of the heart, encompasses a number of different diseases with diverse etiologies and variable clinical presentations. This chapter reviews the definition of myocarditis as per traditional criteria and briefly discusses newer criteria being applied. The roles of clinical history, laboratory diagnostics, electrocardiography, echocardiography, radiology, and biopsy in making a diagnosis of myocarditis are discussed. Each of the common histologic presentations of myocarditis is discussed with respect to the appearance under the microscope and with respect to clinical etiology. These etiologies are then discussed in terms of pathophysiology and the most common presentations observed. The chapter closes with a brief discussion on treatment of myocarditis. © 2022 Elsevier Inc. All rights reserved.