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SARS-CoV-2 Infection-Of Music and Mechanics of Its Spikes! A Perspective.
Kolel-Veetil, Manoj K; Kant, Aayush; Shenoy, Vivek B; Buehler, Markus J.
  • Kolel-Veetil MK; Chemistry Division, Naval Research Laboratory, Washington, D.C. 20375, United States.
  • Kant A; NSF Science and Technology Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • Shenoy VB; NSF Science and Technology Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • Buehler MJ; Laboratory for Atomistic and Molecular Mechanics (LAMM), Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
ACS Nano ; 16(5): 6949-6955, 2022 05 24.
Article in English | MEDLINE | ID: covidwho-1829974
ABSTRACT
The COVID-19 pandemic has been inflicted upon humanity by the SARS-CoV-2 virus, the latest insidious incarnation of the coronaviruses group. While in its wake intense scientific research has produced breakthrough vaccines and cures, there still exists an immediate need to further understand the origin, mechanobiology and biochemistry, and destiny of this virus so that future pandemics arising from similar coronaviruses may be contained more effectively. In this Perspective, we discuss the various evidential findings of virus propagation and connect them to respective underpinning cellular biomechanical states leading to corresponding manifestations of the viral activity. We further propose avenues to tackle the virus, including from a "musical" vantage point, and contain its relentless strides that are currently afflicting the global populace.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Music Topics: Vaccines Limits: Humans Language: English Journal: ACS Nano Year: 2022 Document Type: Article Affiliation country: Acsnano.1c11491

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Music Topics: Vaccines Limits: Humans Language: English Journal: ACS Nano Year: 2022 Document Type: Article Affiliation country: Acsnano.1c11491