Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.

Ju, Bin; Zheng, Qingbing; Guo, Huimin; Fan, Qing; Li, Tingting; Song, Shuo; Sun, Hui; Shen, Senlin; Zhou, Xinrong; Xue, Wenhui; Cui, Lingyan; Zhou, Bing; Li, Shaowei; Xia, Ningshao; Zhang, Zheng

Ju, Bin; Zheng, Qingbing; Guo, Huimin; Fan, Qing; Li, Tingting; Song, Shuo; Sun, Hui; Shen, Senlin; Zhou, Xinrong; Xue, Wenhui; Cui, Lingyan; Zhou, Bing; Li, Shaowei; Xia, Ningshao; Zhang, Zheng.

Ju B; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China. jubin2013@163.com.
Zheng Q; Guangdong Key laboratory for anti-infection Drug Quality Evaluation, Shenzhen, Guangdong, China. jubin2013@163.com.
Guo H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Fan Q; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, China.
Li T; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Song S; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Sun H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Shen S; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, China.
Zhou X; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Xue W; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Cui L; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, China.
Zhou B; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Li S; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Xia N; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Zhang Z; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, China.

Cell Res ; 32(5): 491-494, 2022 05.

Article in English | MEDLINE | ID: covidwho-1830040

Subject(s)

COVID-19; SARS-CoV-2; Antibodies, Neutralizing; Broadly Neutralizing Antibodies; Humans

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Randomized controlled trials Topics: Variants Limits: Humans Language: English Journal: Cell Res Year: 2022 Document Type: Article Affiliation country: S41422-022-00638-6

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