Paracentral acute middle maculopathy in Susac syndrome after dual exposure to SARS-CoV-2 antigen.
BMJ Case Rep
; 15(5)2022 May 10.
Article
in English
| MEDLINE | ID: covidwho-1832380
ABSTRACT
We report a case of Susac syndrome after SARS-CoV-2 infection and subsequent vaccination that presented with meningitis and retinal microembolisation in the form of paracentral acute middle maculopathy (PAMM). After presenting with headache, fever and myalgia followed by scotomata, a woman in her 50s was hospitalised for meningitis; she had had mild COVID-19 infection 2 months prior to admission, having received the first vaccine dose 1 month prior to the neurological manifestation. Eye fundus examination and optical coherence tomography were suggestive of PAMM. D-dimer levels and erythrocyte sedimentation rate were elevated. Before infectious investigation results were available, she was started on empirical antibiotic and antiviral treatment. Having ruled out infectious causes, she was started on high-dose prednisolone. After 1 month, there was partial resolution of retinal lesions. This case highlights that exposure to SARS-CoV-2 antigen may be related to this rare syndrome; treatment with steroids may improve central and retinal impairment.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Retinal Diseases
/
Susac Syndrome
/
COVID-19
/
Macular Degeneration
Type of study:
Case report
/
Diagnostic study
Topics:
Long Covid
/
Vaccines
Limits:
Female
/
Humans
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Bcr-2021-247159
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