Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection: CMAJ
Canadian Medical Association. Journal
; 192(24):E647-E650, 2020.
Article
in English
| ProQuest Central | ID: covidwho-1833682
ABSTRACT
Kirtsman et al discuss the probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. They present a case study of a 40-year-old woman who was admitted to a tertiary hospital in Toronto, Ontario. She had familial neutropenia, gestational diabetes and a history of frequent bacterial infections during pregnancy, which resolved with antibiotic treatment. Details of the maternal course and outcome have been published separately because of her hematologic condition. A nasopharyngeal swab was positive for suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene targets via reverse transcription polymerase chain reaction (RT-PCR) testing. There were no fetal concerns during the pregnancy or following admission. A semiurgent cesarean delivery was done under regional anesthesia, with airborne, droplet and contact precautions, owing to worsening coagulopathy and reducing platelet count at 35 weeks. Artificial rupture of membranes was performed at operation. The male neonate was vigorous and did not require resuscitation. His Apgar scores were 9 at 1 minute and 9 at 5 minutes, but all 3 of the neonate's nasopharyngeal swabs were positive for SARS-CoV-2 gene targets via RT-PCR testing.
Medical Sciences; Infections; Placenta; RNA polymerase; Vagina; Severe acute respiratory syndrome coronavirus 2; Amniotic fluid; Glucose; Skin; Neutropenia; Viral infections; Genes; Breastfeeding & lactation; Enzymes; Coronaviruses; Disease transmission; COVID-19; Congenital diseases; Newborn babies
Full text:
Available
Collection:
Databases of international organizations
Database:
ProQuest Central
Language:
English
Journal:
Canadian Medical Association. Journal
Year:
2020
Document Type:
Article
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