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Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19.
Osawa, Kenta; Sugiyama, Atsuhiko; Uzawa, Akiyuki; Hirano, Shigeki; Yamamoto, Tatsuya; Nezu, Masahiko; Araki, Nobuyuki; Kano, Hiroki; Kuwabara, Satoshi.
  • Osawa K; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Sugiyama A; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Uzawa A; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Hirano S; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Yamamoto T; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Nezu M; Department of Rehabilitation, Division of Occupational Therapy, Chiba Prefectural University of Health Sciences, Japan.
  • Araki N; Department of Kampo Medicine, Chiba University Hospital, Japan.
  • Kano H; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
  • Kuwabara S; Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
Intern Med ; 61(7): 1071-1076, 2022 Apr 01.
Article in English | MEDLINE | ID: covidwho-1834094
ABSTRACT
Myoclonus and ataxia, with or without opsoclonus, have recently been recognized as a central nervous system syndrome associated with coronavirus disease-2019 (COVID-19). A 52-year-old Japanese man developed myoclonus and ataxia 16 days after the onset of COVID-19. Brain single-photon emission computed tomography (SPECT) revealed hyperperfusion in the cerebellum and hypoperfusion in the cerebral cortices with frontal predominance during the acute stage, which improved over two months. This study indicates that brain perfusion SPECT can be effective in detecting functional alterations in COVID-19-related myoclonus and ataxia.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Opsoclonus-Myoclonus Syndrome / COVID-19 / Myoclonus Type of study: Case report Topics: Long Covid Limits: Humans / Male / Middle aged Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.9171-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Opsoclonus-Myoclonus Syndrome / COVID-19 / Myoclonus Type of study: Case report Topics: Long Covid Limits: Humans / Male / Middle aged Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.9171-21