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[Clinical and histopathological patterns of dermatosis in COVID-19 positive patients treated in the Unidad Médica de Alta Especialidad del Bajío, IMSS-T1, de León, Guanajuato]. / Patrones clínicos e histopatológicos de dermatosis en pacientes con infección por COVID-19 en la Unidad Médica de Alta Especialidad del Bajío, IMSS-T1, de León, Guanajuato.
Sánchez-Cárdenas, Carlos D; Farías-Hernández, Mauricio; Verazaluce-Rodríguez, Blanca E; Galván-Linares, Aldo I; Moreno-Coutiño G, Gabriela.
  • Sánchez-Cárdenas CD; Departamento de Medicina Interna, Centro Médico Nacional del Bajío IMSS T1, Unidad Médica de Alta Especialidad, México.
  • Farías-Hernández M; Departamento de Medicina Interna, Centro Médico Nacional del Bajío IMSS T1, Unidad Médica de Alta Especialidad, México.
  • Verazaluce-Rodríguez BE; Departamento de Medicina Interna, Centro Médico Nacional del Bajío IMSS T1, Unidad Médica de Alta Especialidad, México.
  • Galván-Linares AI; Departamento de Medicina Interna, Centro Médico Nacional del Bajío IMSS T1, Unidad Médica de Alta Especialidad, México.
  • Moreno-Coutiño G G; Sección de Micología, Hospital General "Dr. Manuel Gea González" Ciudad de México, México.
Rev Chilena Infectol ; 38(6): 745-753, 2021 12.
Article in Spanish | MEDLINE | ID: covidwho-1835029
ABSTRACT

BACKGROUND:

COVID-19 disease, besides presenting respiratory manifestations, can affect other organs such as kidneys, gastrointestinal system, heart, and skin. So far, five clinical variants of dermatoses have been described. Few reports discuss the severity associated with the cutaneous manifestations of COVID-19 and the prognosis.

AIM:

To describe the clinical and histopathological patterns of dermatoses in patients with COVID-19 infection. PATIENTS AND

METHODS:

Prospective cohort study conducted in patients admitted to "IMSS T1" in Leon, Guanajuato, Mexico from September 2020 to January 2021. We identified those with COVID-19 dermatosis from the moment they were admitted; and those who developed them during hospitalization. Patients were invited to participate for a clinical evaluation and biopsy. The biopsies were described by an expert pathologist.

RESULTS:

The frequency of dermatological lesions was 15.7%. Those who developed dermatosis during their hospital stay presented higher mortality (p = 0.001) and severity of COVID-19 (p = 0.001) Vasoocclusive lesions were the most frequent in the hospital setting, and were associated to higher mortality (p = 0.003). The most frequent histopathological feature was superficial and deep thrombosis (58%).

CONCLUSIONS:

Patients who developed dermatologic lesions during hospitalization and those with vaso-occlusive dermatoses had higher morbi-mortality. Vaso-occlusive lesions could be considered as a poor prognostic factor.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Skin Diseases / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Variants Limits: Humans Language: Spanish Journal: Rev Chilena Infectol Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Skin Diseases / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Variants Limits: Humans Language: Spanish Journal: Rev Chilena Infectol Year: 2021 Document Type: Article