Impact of frailty and viral load on acute kidney injury evolution in patients affected by Coronavirus Disease 2019.
Saudi J Kidney Dis Transpl
; 32(5): 1356-1364, 2021.
Article
in English
| MEDLINE | ID: covidwho-1835076
ABSTRACT
This paper describes the main characteristics of coronavirus diseases 2019 (COVID-19) patients suffering from acute kidney injury (AKI) assisted at a high complexity clinic in Barranquilla, Colombia. The patients included in this study (n = 48) were those with a positive diagnosis of COVID-19 confirmed by polymerase chain reaction detection of severe acute respiratory syndrome coronavirus 2, who had developed AKI during their hospital stay. Serum and urine parameters, as well as patient's viral load and clinical frailty scale (CFS) were recorded. A statistical analysis of the recorded parameters, such as comparisons, and correlations between variables of interest, were explored. The prevalence of COVID-19 induced AKI was 41%, being the majority of them classified as AKI network classification 3, with a renal replacement therapy requirement of 29%, and an associated mortality of 73%. AKI patients' mortality showed a significant positive correlation (33%) with patients' CFS score but not with their viral load. COVID-19 induced AKI significantly correlated with patients' frailty status but not to their viral load.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Fatigue Syndrome, Chronic
/
Acute Kidney Injury
/
Frailty
/
COVID-19
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Saudi J Kidney Dis Transpl
Year:
2021
Document Type:
Article
Affiliation country:
1319-2442.344755
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