Epidemiological and clinical characteristics of patients with COVID-19 in Islamic Republic of Iran.

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) is a worldwide public health emergency. Aims: This study aimed to investigate the epidemiological and clinical characteristics of patients with COVID-19 in Saveh city, Islamic Republic of Iran in 2020. Methods: In this descriptive analytical research, 3181 patients suspected of having COVID-19 who visited Saveh medical centres were investigated. Patients were confirmed with COVID-19 using polymerase chain reaction testing. Data on sociodemographic, epidemiological and clinical characteristics of the patients were collected using a validated form through interviews and medical records. The chi-squared, t and Fisher exact tests were used to assess differences in sociodemographic, epidemiological and clinical characteristics between patients with positive and negative polymerase chain reaction results. Logistic regression analysis was used to examine the association between independent variables and death from COVID-19. Results: About half the patients (48.3%) had a history of chronic disease. Diabetes (16.2%), high blood pressure (14.8%) and cardiovascular disease (12.4%) were the most prevalent chronic diseases among patients who were confirmed positive for COVID-19. Risk factors for death among confirmed COVID-19 patients were intubation (odds ratio (OR) = 8.97; 95% confidence interval (CI) 5.15-15.63), age ≥ 80 years (OR = 5.81; 95% CI 1.91-17.60), oxygen saturation < 93% (OR = 2.48; 95% CI 1.51-4.08), diabetes (OR = 1.88; 95% CI 1.00-3.54) and shortness of breath (OR = 1.70; 95% CI 1.02-2.82). Conclusion: Given the greater risks of contracting and dying from COVID-19 in certain groups of patients, health education programmes targeting these groups are recommended.