General overview on SARS-CoV-2 and potential role of natural compounds as antiviral drugs targeting SARS-CoV-2 proteins. (Special issue.)
Arab Gulf Journal of Scientific Research
; 39(Special Issue (2):15-36, 2021.
Article
in English
| CAB Abstracts | ID: covidwho-1837230
ABSTRACT
Purpose:
The novel coronavirus disease namely COVID-19 is a viral disease induced by severe acute respiratory syndrome coronavirus (SARS-CoV-2). The cases were first reported in Wuhan, China, by the end of 2019 and subsequently spread worldwide. The virus can be transferred through direct or indirect contact and leads to several manifestations;the most common are fever, dry cough, pneumonia, and acute respiratory distress syndrome (ARDS). COVID-19 has caused massive human and economic losses, posing an ongoing threat. Understanding the current situation and developing a treatment which can be both safe and effective has become essential. In this regard, natural products could be an important resource in the development of treatment for COVID-19, as they have contributed to the treatment of other viruses in the past. This review aims to understand the cellular machinery of SARS-CoV-2 and to identify its drug targets.
Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Pesticides and Drugs; Control [HH405]; Nutrition related Disorders and Therapeutic Nutrition [VV130]; human diseases; viral diseases; coronavirus disease 2019; pandemics; antiviral properties; in vitro; reviews; immune response; proteins; antiviral agents; drug therapy; drug targets; viral proteins; natural products; surveys; retinol; ascorbic acid; vitamin B complex; vitamins; vitamin E; enzymes; viral replication; minerals; zinc; selenium; magnesium; Severe acute respiratory syndrome coronavirus 2; man; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; in vivo; SARS-CoV-2; viral infections; anti-viral properties; immunity reactions; immunological reactions; antivirals; chemotherapy; axerophthol; vitamin A; vitamin A alcohol; vitamin A1; vitamin C; vitamin B
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Arab Gulf Journal of Scientific Research
Year:
2021
Document Type:
Article
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