Phytochemical screening, GCMS profile, and in-silico properties of bioactive compounds in methanolic leaf extracts of Moringa oleifera
Journal of Drug Delivery and Therapeutics
; 12(2):87-99, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-1841785
ABSTRACT
Plant Based Natural Products (PBNPs) have been subject of interest since ancient time due to their use in food, industrial and biomedical applications. Research attention has further augmented to explore their phytochemical composition, properties, and potential application in the post-COVID era. In the present study phytochemical screening has been carried out with Methanolic Leaf Extracts of Moringa oleifera (MLEMO) followed by Gas Chromatography-Mass Spectrometry (GCMS) analysis. Phytochemical analysis of MLEMO revealed the presence of Alkaloids, Carbohydrates, Coumarins, Flavonoids, Glycosides, Phenol, Proteins, Quinones, Saponins, Steroids, Tannins and Terpenoids. Further, GCMS analysis revealed the presence of 41 compounds of which Dihydroxyacetone;Monomethyl malonate;4H-Pyran-4-one,2,3-dihydro- 3,5-dihydroxy-6-methyl;1,3-Propanediol, 2-ethyl-2-(hydroxymethyl);Propanoic acid, 2- methyl-, octyl ester;3-Deoxy-d-mannoic lactone;Sorbitol;Inositol;Cyclohexanemethanol, alpha-methyl-4-(1-methylethyl), Hexadecanoic acid, Methyl palmitate;n-Hexadecanoic acid (Palmitic acid);9-Octadecenoic acid, methyl ester;Phytol;9,12,15-Octadecatrienoic acid;Octadecanoic acid;9-Octadecenamide were prominent. Most of the compounds in the list are bioactive and possess medicinal properties that are expected to serve as a baseline lead for the development of therapeutic agents.
Horticultural Crops [FF003]; Plant Composition [FF040]; Forests and Forest Trees (Biology and Ecology) [KK100]; Non-food/Non-feed Plant Products [SS200]; chemical composition; plant composition; terpenoids; alkaloids; biological activity; carbohydrates; coumarins; flavonoids; glycosides; ketones; leaves; medicinal properties; myo-inositol; oleic acid; palmitic acid; phenolic compounds; phytol; plant extracts; propionic acid; quinones; saponins; sorbitol; stearic acid; steroids; tannins; phenols; protein content; Moringa oleifera; Moringa; Moringaceae; Brassicales; eudicots; angiosperms; Spermatophyta; plants; eukaryotes; chemical constituents of plants; terpenes; bioactivity; saccharides; heterosides; inositol; meso-inositol; hexadecanoic acid; propanoic acid; octadecanoic acid; tannic acid
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Journal of Drug Delivery and Therapeutics
Year:
2022
Document Type:
Article
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